Certificate of Analysis


Catalog Number: M6199
Product Name: MSC2530818
CAS Number: 1883423-59-3

Physical and Chemical Properties
Formula: C18H17ClN4O
Molecular Weight: 340.81
Solubility: 68 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: MSC2530818 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: MSC2530818, a CDK8 inhibitor with the IC50 of 2.6 nM, displays excellent kinase selectivity, biochemical and cellular potency, microsomal stability, and is orally bioavailable.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.