Certificate of Analysis
| Product Name: | MSC2530818 |
| Catalog Number: | M6199 |
| CAS Number: | 1883423-59-3 |
Physical and Chemical Properties
| Formula: | C18H17ClN4O |
| Molecular Weight: | 340.81 |
| Solubility: | 68 mg/mL in DMSO |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.16% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MSC2530818, a CDK8 inhibitor with the IC50 of 2.6 nM, displays excellent kinase selectivity, biochemical and cellular potency, microsomal stability, and is orally bioavailable. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |