Certificate of Analysis

 

Catalog Number: M3518
Product Name: MK-8245
CAS Number: 1030612-90-8

Physical and Chemical Properties
Formula: C17H16BrFN6O4
Molecular Weight: 467.25
Solubility: DMSO 90 mg/mL
Long-term Storage: at -20℃
Chemical Structure: MK-8245 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.