Certificate of Analysis

 

Product Name: MK-0974
Catalog Number: M3618
CAS Number: 781649-09-0

Physical and Chemical Properties
Formula: C26H27F5N6O3
Molecular Weight: 566.52
Solubility: DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: MK-0974 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: MK-0974 (Telcagepant) is a highly potent, selective and orally bioavailable CGRP receptor antagonist with Ki values of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.