Certificate of Analysis

 

Catalog Number: M5258
Product Name: Mivebresib
CAS Number: 1445993-26-9

Physical and Chemical Properties
Formula: C22H19F2N3O4S
Molecular Weight: 459.47
Solubility: 91 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Mivebresib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Mivebresib(ABBV-075) is a novel BET family bromodomain inhibitor. It binds bromodomains of BRD2/4/T with similar affinities (Ki of 1-2.2 nM) and highly selective for 18 bromodomain proteins tested (Kd > 1 μM; more than 600-fold selectivity vs. BRD4)
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.