Certificate of Analysis

 

Product Name: Midostaurin
Catalog Number: M2850
CAS Number: 120685-11-2

Physical and Chemical Properties
Formula: C35H30N4O4
Molecular Weight: 570.64
Solubility: DMSO 29 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Midostaurin  Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Midostaurin (pkc412) is a multi-targeted kinase inhibitor, including PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 ranging from 80-500 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.