Certificate of Analysis


Catalog Number: M5221
Product Name: MG-101
CAS Number: 110044-82-1

Physical and Chemical Properties
Formula: C20H37N3O4
Molecular Weight: 383.53
Solubility: 76mg/ml in DMSO
Long-term Storage: at -20°C
Chemical Structure: MG-101 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: MG-101 is a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM). IC50 value: 150 nM (Ki)
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.