Certificate of Analysis

 

Catalog Number: M4889
Product Name: LEE011 succinate
CAS Number: 1374639-75-4

Physical and Chemical Properties
Formula: C27H36N8O5
Molecular Weight: 552.63
Solubility: 10 mM in DMSO
Long-term Storage: at -20°C
Chemical Structure: LEE011 succinate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: LEE011 succinate is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.