Certificate of Analysis

 

Catalog Number: M2805
Product Name: LDN-193189 hydrochloride
CAS Number: 1062368-62-0

Physical and Chemical Properties
Formula: C25H22N6.HCl
Molecular Weight: 442.94
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: LDN-193189 hydrochloride Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: LDN193189 hydrochloride is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, 200-fold selectivity for BMP versus TGF-β.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.