|Product Name:||LDK378 dihydrochloride|
|Solubility:||170 mg/mL in water|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min 99.81% purity|
|H-NMR:||Consistent with structure|
|Description:||LDK378 2Hcl (Ceritinib) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.