Certificate of Analysis


Catalog Number: M2338
Product Name: LDE225
CAS Number: 956697-53-3

Physical and Chemical Properties
Formula: C26H26F3N3O3
Molecular Weight: 485.5
Solubility: DMSO 80 mg/mL, Ethanol 80 mg/mL
Long-term Storage: at -20°C
Chemical Structure: LDE225 Structure
Analytical Data
HPLC: Shows Min 100.00% purity
H-NMR: Consistent with structure
Product Information
Description: LDE225 (NVP-LDE225) is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.