|Solubility:||DMSO 80 mg/mL, Ethanol 80 mg/mL|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min 100.00% purity|
|H-NMR:||Consistent with structure|
|Description:||LDE225 (NVP-LDE225) is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.