Certificate of Analysis


Catalog Number: M5327
Product Name: L-779450
CAS Number: 303727-31-3

Physical and Chemical Properties
Formula: C20H14ClN3O
Molecular Weight: 347.8
Solubility: ≥ 34 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: L-779450 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: L-779450 is a potent, ATP-competitive Raf kinase inhibitor (IC50 =10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.