|Solubility:||≥ 34 mg/mL in DMSO|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min >98% purity|
|H-NMR:||Consistent with structure|
|Description:||L-779450 is a potent, ATP-competitive Raf kinase inhibitor (IC50 =10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.