Certificate of Analysis

 

Catalog Number: M2798
Product Name: KU-0060648
CAS Number: 881375-00-4

Physical and Chemical Properties
Formula: C33H34N4O4S
Molecular Weight: 582.71
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: KU-0060648 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.