Certificate of Analysis


Catalog Number: M2587
Product Name: JW55
CAS Number: 664993-53-7

Physical and Chemical Properties
Formula: C25H26N2O5
Molecular Weight: 434.48
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: JW55 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: JW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.