Certificate of Analysis


Catalog Number: M5028
Product Name: JANEX-1
CAS Number: 202475-60-3

Physical and Chemical Properties
Formula: C16H15N3O3
Molecular Weight: 297.31
Solubility: DMSO:~1 mg/ml
Long-term Storage: at -20°C
Chemical Structure: JANEX-1 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78 μM); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.