Certificate of Analysis

 

Catalog Number: M2782
Product Name: IWR-1-endo
CAS Number: 1127442-82-3

Physical and Chemical Properties
Formula: C25H19N3O3
Molecular Weight: 409.44
Solubility: DMSO 20 mg/mL
Long-term Storage: at -20℃
Chemical Structure: IWR-1-endo Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: IWR-1 (endo-IWR 1) is a Wnt pathway inhibitor with IC50 of 180 nM, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.