Certificate of Analysis
| Product Name: | Itacitinib |
| Catalog Number: | M8876 |
| CAS Number: | 1334298-90-6 |
Physical and Chemical Properties
| Formula: | C26H23F4N9O |
| Molecular Weight: | 553.51 |
| Solubility: | DMSO: ≥ 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.53% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Itacitinib (INCB039110) is a potent, selective JAK1 inhibitor with an IC50 value of 2 nM for human JAK1. It has oral bioactivity and potential anti-tumor activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |