Certificate of Analysis

 

Product Name: Olverembatinib
Catalog Number: M6305
CAS Number: 1257628-77-5

Physical and Chemical Properties
Formula: C29H27F3N6O
Molecular Weight: 532.56
Solubility: 100 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Olverembatinib Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Olverembatinib is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.