Certificate of Analysis

 

Catalog Number: M2745
Product Name: GW5074
CAS Number: 220904-83-6

Physical and Chemical Properties
Formula: C15H8Br2INO2
Molecular Weight: 520.94
Solubility: DMSO 90 mg/mL
Long-term Storage: at -20℃
Chemical Structure: GW5074 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.