Certificate of Analysis

 

Product Name: GW5074
Catalog Number: M2745
CAS Number: 220904-83-6

Physical and Chemical Properties
Formula: C15H8Br2INO2
Molecular Weight: 520.94
Solubility: DMSO 90 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: GW5074 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.