Certificate of Analysis


Catalog Number: M5271
Product Name: GSK6853
CAS Number: 1910124-24-1

Physical and Chemical Properties
Formula: C22H27N5O3
Molecular Weight: 409.48
Solubility: 81 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: GSK6853 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: GSK6853 is a selective benzimidazolone BRPF1 inhibitor with pIC50 of 8.1(TR-FRET) showing greater than 1600-fold selectivity over all other bromodomains tested.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.