Certificate of Analysis

 

Product Name: GSK2656157
Catalog Number: M2735
CAS Number: 1337532-29-2

Physical and Chemical Properties
Formula: C23H21FN6O
Molecular Weight: 416.45
Solubility: DMSO 20 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: GSK2656157 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM, 500-fold greater against a panel of 300 kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.