Certificate of Analysis

 

Product Name: GSK1324726A
Catalog Number: M9146
CAS Number: 1300031-52-0

Physical and Chemical Properties
Formula: C25H23ClN2O3
Molecular Weight: 434.91
Solubility: DMSO: ≥ 43 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: GSK1324726A Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: GSK1324726A (I-BET726) is a highly selective inhibitor of BET family proteins with IC50 of 41 nM, 31 nM, and 22 nM for BRD2, BRD3, and BRD4, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.