Certificate of Analysis

 

Catalog Number: M2585
Product Name: GNF-5837
CAS Number: 1033769-28-6

Physical and Chemical Properties
Formula: C28H21F4N5O2
Molecular Weight: 535.49
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: GNF-5837 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: GNF-5837 is a potent pan-Trk inhibitor which display antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.