Certificate of Analysis


Catalog Number: M6226
Product Name: GNE-477
CAS Number: 1032754-81-6

Physical and Chemical Properties
Formula: C21H28N8O3S2
Molecular Weight: 504.63
Solubility: 9.2 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: GNE-477 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: GNE-477 is a potent and efficacious dual PI3K (IC50=4 nM)/mTOR(Ki=21 nM) inhibitor.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.