Certificate of Analysis

 

Catalog Number: M5679
Product Name: Gefitinib HCl
CAS Number: 184475-55-6

Physical and Chemical Properties
Formula: C22H25Cl2FN4O3
Molecular Weight: 483.36
Solubility: 10 mM in DMSO
Long-term Storage: at -20℃
Chemical Structure: Gefitinib HCl Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Gefitinib Hcl(ZD-1839 Hcl) is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.