Certificate of Analysis

 

Product Name: GDC-0853 (Fenebrutinib)
Catalog Number: M8941
CAS Number: 1434048-34-6

Physical and Chemical Properties
Formula: C37H44N8O4
Molecular Weight: 664.8
Solubility: DMSO ≥ 20 mg/mL
Storage: 2-8°C, sealed
Chemical Structure: GDC-0853 (Fenebrutinib) Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: GDC-0853 (Fenebrutinib) is a potent, selective and non-covalent bruton tyrosine kinase (Btk) inhibitor with a Ki value of 0.91 nM against BRK.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.