Certificate of Analysis

 

Product Name: Ipatasertib (GDC-0068)
Catalog Number: M1862
CAS Number: 1001264-89-6

Physical and Chemical Properties
Formula: C24H32ClN5O2
Molecular Weight: 458
Solubility: DMSO 90 mg/mL; Ethanol 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Ipatasertib (GDC-0068) Structure
Analytical Data
QC Standard: 99.25%
H-NMR: Consistent with structure
Product Information
Description: GDC-0068 (RG7440) is a potent and selective, ATP-competitive Akt inhibitor with IC50 values of 5 to 18 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.