Certificate of Analysis

 

Product Name: Gartisertib
Catalog Number: M11251
CAS Number: 1613191-99-3

Physical and Chemical Properties
Formula: C25H29F2N9O3
Molecular Weight: 541.55
Solubility: DMSO ≥ 10 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Gartisertib Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Gartisertib (VX-803) is an ATP-competitive, orally active, selective ATR inhibitor with Ki<150 pM. Gartisertib inhibits atR-driven phosphorylation of checkpoint kinase-1 (Chk1) with an IC50 value of 8 nM. It has antitumor activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.