Certificate of Analysis

 

Catalog Number: M5142
Product Name: G-749
CAS Number: 1457983-28-6

Physical and Chemical Properties
Formula: C25H25BrN6O2
Molecular Weight: 521.41
Solubility:
Long-term Storage: at -20℃
Chemical Structure: G-749 Structure
Analytical Data
HPLC: Shows Min purity
H-NMR: Consistent with structure
Product Information
Description: G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.