Certificate of Analysis
| Product Name: | Fruquintinib |
| Catalog Number: | M7554 |
| CAS Number: | 1194506-26-7 |
Physical and Chemical Properties
| Formula: | C21H19N3O5 |
| Molecular Weight: | 393.39 |
| Solubility: | 7.75 mg/mL in DMSO |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.90% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0.35, and 35 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |