Certificate of Analysis
| Product Name: | Firibastat |
| Catalog Number: | M21495 |
| CAS Number: | 648927-86-0 |
Physical and Chemical Properties
| Formula: | C8H20N2O6S4 |
| Molecular Weight: | 368.51 |
| Solubility: | Wate ≥ 20 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ＞98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Firibastat (QGC001) is an orally active EC33 precursor drug. Firibastat is A first-in-class (first-in-class) brain aminopeptidase A (APA) inhibitor (Ki=200 nM) that selectively and specifically inhibits the conversion of cerebral angiotensin II to angiotensin III and lowers blood pressure in hypertensive rats. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |