Certificate of Analysis

 

Product Name: Filgotinib
Catalog Number: M2346
CAS Number: 1206161-97-8

Physical and Chemical Properties
Formula: C21H23N5O3S
Molecular Weight: 425.5
Solubility: DMSO 20 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Filgotinib Structure
Analytical Data
QC Standard: 98.65%
H-NMR: Consistent with structure
Product Information
Description: Filgotinib (GLPG0634) is the first selective inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.