Certificate of Analysis

 

Product Name: EPZ005687
Catalog Number: M2676
CAS Number: 1396772-26-1

Physical and Chemical Properties
Formula: C32H37N5O3
Molecular Weight: 539.67
Solubility: DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: EPZ005687 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: EPZ005687 is a potent, selective EZH2 inhibitor,Ki The value is 24 nM, which is 50 times more selective than EZH1 and 500 times more selective than 15 other methyltransferases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.