Certificate of Analysis

 

Catalog Number: M2677
Product Name: EPZ-6438
CAS Number: 1403254-99-8

Physical and Chemical Properties
Formula: C34H44N4O4
Molecular Weight: 572.74
Solubility: DMSO 10 mg/mL
Long-term Storage: at -20℃
Chemical Structure: EPZ-6438 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: EPZ-6438 is a potent, and selective EZH2 inhibitor with Ki and IC50 of 2.5 nM and 11 nM, exhibiting a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other HMTs.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.