Certificate of Analysis


Catalog Number: M6136
Product Name: Epacadostat
CAS Number: 1204669-58-8

Physical and Chemical Properties
Formula: C11H13BrFN7O4S
Molecular Weight: 438.23
Solubility: 87 mg/mL in DMSO
Storage: at -20°C
Chemical Structure: Epacadostat Structure
Analytical Data
HPLC: Shows Min 98.49% purity
H-NMR: Consistent with structure
Product Information
Description: Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.