Certificate of Analysis

 

Product Name: E-7046
Catalog Number: M6138
CAS Number: 1369489-71-3

Physical and Chemical Properties
Formula: C22H18F5N3O4
Molecular Weight: 483.39
Solubility: DMSO: ≥ 35 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: E-7046 Structure
Analytical Data
QC Standard: 99.49%
H-NMR: Consistent with structure
Product Information
Description: E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.