Certificate of Analysis

 

Catalog Number: M3484
Product Name: Dolutegravir
CAS Number: 1051375-16-6

Physical and Chemical Properties
Formula: C20H19F2N3O5
Molecular Weight: 419.38
Solubility: DMSO 80 mg/mL
Long-term Storage: at -20℃
Chemical Structure: Dolutegravir Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: S/GSK1349572 (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.