Certificate of Analysis

 

Catalog Number: M1869
Product Name: Dacomitinib
CAS Number: 1110813-31-4

Physical and Chemical Properties
Formula: C24H25ClFN5O2
Molecular Weight: 469.94
Solubility: DMSO ≥20 mg/mL
Long-term Storage: at -20℃
Chemical Structure: Dacomitinib Structure
Analytical Data
HPLC: Shows Min 99.74% purity
H-NMR: Consistent with structure
Product Information
Description: Dacomitinib (PF-00299804) is an oral, irreversible, small molecule inhibitor of human epidermal growth factor receptor-1, -2, and -4 tyrosine kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.