Certificate of Analysis

 

Product Name: CX-6258 HCl
Catalog Number: M5321
CAS Number: 1353859-00-3

Physical and Chemical Properties
Formula: C26H24ClN3O3.HCl
Molecular Weight: 498.40
Solubility: 57 mg/mL warmed in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: CX-6258 HCl  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.