Certificate of Analysis
| Product Name: | CX-5461 |
| Catalog Number: | M2293 |
| CAS Number: | 1138549-36-6 |
Physical and Chemical Properties
| Formula: | C27H27N7O2S |
| Molecular Weight: | 513.61 |
| Solubility: | Water 50 mg/mL (ultrasonic and adjust pH to 2 with HCl); 50 mM sodium phosphate (pH 3.5) : 10 mg/mL (Need ultrasonic) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.50% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | CX-5461 (Pidnarulex) selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116 cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |