Certificate of Analysis


Catalog Number: M2212
Product Name: CO-1686
CAS Number: 1374640-70-6

Physical and Chemical Properties
Formula: C27H28F3N7O3
Molecular Weight: 555.55
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: CO-1686 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: CO-1686 is a potent, novel inhibitor of EGFR L858R/T790M kinase with Ki of 21.5 nM and 303.3 nM, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.