Certificate of Analysis
| Product Name: | Cilofexor |
| Catalog Number: | M9039 |
| CAS Number: | 1418274-28-8 |
Physical and Chemical Properties
| Formula: | C28H23Cl2N3O5 |
| Molecular Weight: | 552.4 |
| Solubility: | DMSO: ≥ 60 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.78% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Cilofexor is a potent, selective, orally active non-steroidal farnesoid X receptor (FXR) agonist with an EC50 value of 43 nM. It has anti-inflammatory activity and may be studied in primary sclerosing cholangitis (PSC) and non-alcoholic steatohepatitis (NASH). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |