Certificate of Analysis

 

Product Name: CGP 57380
Catalog Number: M2506
CAS Number: 522629-08-9

Physical and Chemical Properties
Formula: C11H9FN6
Molecular Weight: 244.23
Solubility: DMSO 28 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: CGP 57380 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: CGP 57380 is potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.