Certificate of Analysis

 

Product Name: CDKI-73
Catalog Number: M9910
CAS Number: 1421693-22-2

Physical and Chemical Properties
Formula: C15H15FN6O2S2
Molecular Weight: 394.45
Solubility: DMSO 40 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: CDKI-73 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Cdki-73 (LS-007) is an orally active and highly effective CDK9 inhibitor with Ki values of 4 nM, 4 nM and 3 nM against CDK9, CDK1 and CDK2, respectively. Cdki-73 down-regulates phosphorylation of RNA polymerase II. Cdki-73 is also an inhibitor of Rab11.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.