Certificate of Analysis

 

Catalog Number: M3684
Product Name: Canertinib dihydrochloride
CAS Number: 289499-45-2

Physical and Chemical Properties
Formula: C24H27Cl3FN5O3
Molecular Weight: 558.86
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: Canertinib dihydrochloride Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Canertinib 2HCl is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.