Certificate of Analysis

 

Catalog Number: M1943
Product Name: Canertinib
CAS Number: 267243-28-7

Physical and Chemical Properties
Formula: C24H25ClFN5O3
Molecular Weight: 485.94
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: Canertinib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Canertinib (CI-1033) is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (IC50 7 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.