Certificate of Analysis

 

Product Name: BS-181 hydrochloride
Catalog Number: M3504
CAS Number: 1397219-81-6

Physical and Chemical Properties
Formula: C22H32N6.HCl
Molecular Weight: 416.99
Solubility: Water 85 mg/mL; DMSO 45 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: BS-181 hydrochloride Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: BS-181 is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.