Certificate of Analysis

 

Product Name: Bosentan Hydrate
Catalog Number: M2278
CAS Number: 157212-55-0

Physical and Chemical Properties
Formula: C27H29N5O6S.H2O
Molecular Weight: 569.63
Solubility: DMSO 73 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Bosentan Hydrate Structure
Analytical Data
QC Standard: 99.12%
H-NMR: Consistent with structure
Product Information
Description: Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.