Certificate of Analysis

 

Product Name: Bohemine
Catalog Number: M6160
CAS Number: 189232-42-6

Physical and Chemical Properties
Formula: C18H24N6O
Molecular Weight: 340.42
Form: Solid
Solubility: DMSO 80 mg/mL
Storage: Powder -20°C
Chemical Structure: Bohemine Structure
Analytical Data
QC Standard: >98.5%
H-NMR: Consistent with structure
Product Information
Description: Bohemine is A selective CDK inhibitor with IC50 of 4.6 μM, 83 μM and 2.7 μM against Cdk2/ Cyclin E, Cdk2/ Cyclin A and Cdk9/cyclin T1, respectively. Bohemine also inhibited ERK2, IC50 was 52 μM, and inhibited CDK1, CDK4 and CDK6. Bohemine is also a purine analogue and has a wide range of anticancer activities.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.