Certificate of Analysis

 

Catalog Number: M2466
Product Name: BMS-911543
CAS Number: 1271022-90-2

Physical and Chemical Properties
Formula: C23H28N8O
Molecular Weight: 432.52
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: BMS-911543 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.