Certificate of Analysis

 

Product Name: BMS-777607
Catalog Number: M1682
CAS Number: 1196681-44-3

Physical and Chemical Properties
Formula: C25H19ClF2N4O4
Molecular Weight: 512.89
Solubility: DMSO 40 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: BMS-777607 Structure
Analytical Data
QC Standard: 99.50%
H-NMR: Consistent with structure
Product Information
Description: BMS-777607 is a selective and potent small-molecule met kinase inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.